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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | RBI | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Al Simmons* | 176 | 1925 | |
| 2 | Stan Musial# | 164 | 1945 | |
| 3 | Hugh Duffy* | 145 | 1894 | |
| 4 | Oscar Charleston* | 144 | 1922 | |
| 5 | Willie Mays# | 141 | 1954 | |
| 6 | Al Simmons* | 139 | 1926 | |
| 7 | Babe Ruth* | 137 | 1923 | |
| 7 | Larry Doby# | 137 | 1946 | |
| 9 | Oscar Charleston* | 136 | 1926 | |
| 10 | Joe DiMaggio# | 135 | 1938 | |
| 11 | Steve Brodie | 134 | 1895 | |
| 12 | Hack Wilson | 133 | 1930 | |
| 12 | Ty Cobb* | 133 | 1912 | |
| 12 | Heinie Manush | 133 | 1927 | |
| 12 | Joe DiMaggio# | 133 | 1937 | |
| 16 | Joe DiMaggio# | 132 | 1940 | |
| 16 | Willie Mays# | 132 | 1953 | |
| 18 | Oscar Charleston* | 127 | 1921 | |
| 19 | Andy Pafko# | 126 | 1950 | |
| 19 | Oscar Charleston* | 126 | 1920 | |
| 21 | Johnny Frederick | 125 | 1930 | |
| 22 | Al Simmons* | 124 | 1927 | |
| 22 | Earl Averill | 124 | 1934 | |
| 22 | Duke Snider# | 124 | 1953 | |
| 22 | Wally Berger | 124 | 1934 | |
| 26 | Babe Ruth* | 123 | 1924 | |
| 26 | Babe Ruth* | 123 | 1926 | |
| 28 | Stan Musial# | 122 | 1943 | |
| 28 | Joe DiMaggio# | 122 | 1945 | |
| 30 | Babe Ruth* | 121 | 1922 | |
| 30 | Cristobal Torriente | 121 | 1922 | |
| 32 | Baby Doll Jacobson | 120 | 1919 | |
| 32 | Mel Ott* | 120 | 1935 | |
| 32 | Earl Averill | 120 | 1930 | |
| 35 | Turkey Stearnes | 119 | 1929 | |
| 35 | Sam Crawford* | 119 | 1908 | |
| 35 | Mel Ott* | 119 | 1930 | |
| 35 | Cy Seymour* | 119 | 1903 | |
| 39 | Ty Cobb* | 118 | 1911 | |
| 39 | Duke Snider# | 118 | 1950 | |
| 39 | Hugh Duffy* | 118 | 1893 | |
| 39 | Duke Snider# | 118 | 1954 | |
| 43 | Earl Averill | 117 | 1932 | |
| 44 | Turkey Stearnes | 116 | 1928 | |
| 44 | Alejandro Oms | 116 | 1923 | |
| 44 | Larry Doby# | 116 | 1953 | |
| 44 | Henry Kimbro# | 116 | 1946 | |
| 48 | Turkey Stearnes | 115 | 1930 | |
| 48 | Pete Hill | 115 | 1906 | |
| 50 | Monte Irvin# | 114 | 1947 | |
| 50 | Duke Snider# | 114 | 1949 | |
| 50 | Hack Wilson | 114 | 1928 | |
| 50 | Hank Leiber | 114 | 1938 | |
| 54 | Steve Brodie | 113 | 1894 | |
| 54 | Hack Wilson | 113 | 1926 | |
| 54 | Bobby Thomson# | 113 | 1950 | |
| 57 | Pete Hill | 112 | 1913 | |
| 57 | Henry Kimbro# | 112 | 1948 | |
| 57 | Joe DiMaggio# | 112 | 1948 | |
| 57 | Cristobal Torriente | 112 | 1921 | |
| 57 | Monte Irvin# | 112 | 1942 | |
| 62 | Hack Wilson | 111 | 1929 | |
| 62 | Ralph Kiner# | 111 | 1946 | |
| 62 | Frank Thomas# | 111 | 1953 | |
| 65 | Monte Irvin# | 110 | 1945 | |
| 65 | Joe Kelley | 110 | 1898 | |
| 65 | Johnny Frederick | 110 | 1929 | |
| 65 | Joe DiMaggio# | 110 | 1939 | |
| 65 | Mickey Mantle# | 110 | 1953 | |
| 70 | Joe DiMaggio# | 109 | 1950 | |
| 70 | Oscar Charleston* | 109 | 1923 | |
| 70 | Vince DiMaggio# | 109 | 1941 | |
| 70 | Hack Wilson | 109 | 1927 | |
| 70 | Ty Cobb* | 109 | 1913 | |
| 70 | Carl Furillo# | 109 | 1948 | |
| 76 | Joe Jackson* | 108 | 1910 | |
| 76 | Earle Combs | 108 | 1932 | |
| 78 | Max West | 107 | 1942 | |
| 78 | Duke Snider# | 107 | 1951 | |
| 78 | Taylor Douthit | 107 | 1930 | |
| 81 | Sam Crawford* | 106 | 1909 | |
| 82 | Earl Averill | 105 | 1936 | |
| 82 | Ginger Beaumont | 105 | 1906 | |
| 84 | Tris Speaker* | 104 | 1925 | |
| 84 | Johnny Mostil | 104 | 1921 | |
| 84 | Mickey Mantle# | 104 | 1952 | |
| 84 | Stan Musial# | 104 | 1944 | |
| 84 | Mickey Mantle# | 104 | 1954 | |
| 84 | Oscar Charleston* | 104 | 1925 | |
| 84 | Willard Brown# | 104 | 1935 | |
| 84 | Joe DiMaggio# | 104 | 1947 | |
| 84 | George Van Haltren | 104 | 1894 | |
| 84 | Tris Speaker* | 104 | 1914 | |
| 84 | Henry Kimbro# | 104 | 1949 | |
| 84 | Jules Thomas | 104 | 1925 | |
| 96 | Pete Hill | 103 | 1910 | |
| 96 | Tris Speaker* | 103 | 1910 | |
| 96 | George Van Haltren | 103 | 1895 | |
| 96 | Ty Cobb* | 103 | 1910 | |
| 96 | Mike Donlin | 103 | 1905 |
