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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | BB | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Charles Bender# | 37 | 1903-1916 | |
| 2 | Vean Gregg# | 30 | 1911-1916 | |
| 3 | Rube Waddell | 25 | 1897-1910 | |
| 4 | Dutch Leonard# | 20 | 1913-1916 | |
| 5 | Claude Hendrix# | 18 | 1911-1916 | |
| 5 | Christy Mathewson | 18 | 1900-1916 | |
| 7 | Rube Marquard# | 17 | 1908-1916 | |
| 8 | Red Ames# | 16 | 1903-1916 | |
| 9 | Jack Coombs# | 15 | 1906-1916 | |
| 10 | Orval Overall | 14 | 1905-1913 | |
| 10 | Jeff Tesreau# | 14 | 1912-1916 | |
| 12 | Cy Young* | 12 | 1890-1911 | |
| 13 | Frank Lange | 11 | 1910-1913 | |
| 13 | George McConnell | 11 | 1912-1916 | |
| 13 | George McQuillan# | 11 | 1907-1916 | |
| 13 | Joe Wood# | 11 | 1908-1916 | |
| 17 | Bill Bernhard | 10 | 1899-1907 | |
| 17 | Mordecai Brown | 10 | 1903-1916 | |
| 17 | George Mullin | 10 | 1902-1913 | |
| 17 | Eddie Plank# | 10 | 1901-1916 | |
| 17 | Jesse Tannehill | 10 | 1894-1910 | |
| 22 | Jack Chesbro | 9 | 1899-1909 | |
| 22 | Ferdie Schupp# | 9 | 1916-1916 | |
| 24 | Frank Smith | 8 | 1904-1911 | |
| 25 | Otto Hess | 7 | 1902-1914 | |
| 25 | Tom Hughes# | 7 | 1906-1916 | |
| 25 | Win Kellum | 7 | 1901-1905 | |
| 25 | Joe Lake | 7 | 1908-1913 | |
| 25 | Jack Pfiester | 7 | 1904-1911 | |
| 25 | Joe Williams# | 7 | 1907-1916 | |
| 31 | Weldon Henley | 6 | 1903-1907 | |
| 31 | Addie Joss | 6 | 1902-1910 | |
| 31 | Babe Ruth# | 6 | 1914-1916 | |
| 31 | Charlie Smith | 6 | 1903-1914 | |
| 31 | Doc White | 6 | 1901-1912 | |
| 31 | George Winter | 6 | 1901-1908 | |
| 37 | Harry Krause | 5 | 1908-1911 | |
| 37 | Lefty Leifield# | 5 | 1905-1913 | |
| 37 | Earl Moore | 5 | 1901-1913 | |
| 40 | Babe Adams# | 4 | 1906-1916 | |
| 40 | Ray Collins | 4 | 1909-1915 | |
| 40 | George Cuppy | 4 | 1892-1901 | |
| 40 | Marty McHale | 4 | 1913-1916 | |
| 40 | Kid Nichols* | 4 | 1890-1906 | |
| 40 | Jimmy Ryan | 4 | 1885-1903 | |
| 46 | Al Demaree# | 3 | 1912-1916 | |
| 46 | Bill Donovan# | 3 | 1898-1916 | |
| 46 | Rube Foster# | 3 | 1913-1916 | |
| 46 | Tom Hughes | 3 | 1900-1913 | |
| 46 | Carl Mays# | 3 | 1915-1916 | |
| 46 | Jock Menefee | 3 | 1892-1903 | |
| 46 | Deacon Phillippe | 3 | 1899-1911 | |
| 46 | Bill Phyle | 3 | 1898-1906 | |
| 46 | George Prentiss | 3 | 1901-1902 | |
| 46 | Dave Williams | 3 | 1902-1902 | |
| 56 | Fred Anderson# | 2 | 1909-1916 | |
| 56 | Eddie Cicotte# | 2 | 1906-1916 | |
| 56 | Russ Ford | 2 | 1909-1913 | |
| 56 | Ed Killian | 2 | 1903-1910 | |
| 56 | Hank Robinson# | 2 | 1911-1916 | |
| 61 | Gus Dorner | 1 | 1902-1909 | |
| 61 | George Ferguson | 1 | 1906-1910 | |
| 61 | Frank Foreman | 1 | 1884-1902 | |
| 61 | Norwood Gibson | 1 | 1903-1906 | |
| 61 | Sam Leever | 1 | 1898-1909 | |
| 61 | Jack Rowan | 1 | 1906-1914 | |
| 61 | Dummy Taylor | 1 | 1900-1908 | |
| 61 | Hooks Wiltse | 1 | 1904-1914 | |
| 69 | Nick Altrock# | 0 | 1898-1916 | |
| 69 | Joe Bush# | 0 | 1912-1916 | |
| 69 | Frank Corridon | 0 | 1906-1909 | |
| 69 | Cy Falkenberg# | 0 | 1904-1915 | |
| 69 | Ted Lewis | 0 | 1896-1901 | |
| 69 | Fred Mitchell | 0 | 1902-1911 | |
| 69 | Ed Reulbach# | 0 | 1905-1916 | |
| 69 | Ernie Shore# | 0 | 1914-1916 | |
| 69 | Ed Siever | 0 | 1901-1908 | |
| 69 | Paul Strand# | 0 | 1913-1915 | |
| 69 | Snake Wiltse | 0 | 1901-1903 |
