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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | OAVG | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Jumbo Brown | .1837 | 1926-1952 | |
| 2 | Orval Overall | .1855 | 1905-1913 | |
| 3 | Addie Joss* | .1908 | 1902-1910 | |
| 4 | Spud Chandler | .1917 | 1937-1952 | |
| 5 | Hal Schumacher | .1977 | 1931-1947 | |
| 6 | Babe Adams* | .1990 | 1906-1926 | |
| 7 | Charley Root | .2000 | 1923-1940 | |
| 8 | Max Lanier | .2009 | 1938-1951 | |
| 9 | Jesse Tannehill | .2140 | 1894-1910 | |
| 10 | Ed Brandt | .2195 | 1928-1950 | |
| 11 | Tiny Bonham | .2275 | 1940-1950 | |
| 12 | Eddie Plank* | .2319 | 1901-1917 | |
| 13 | Curt Simmons# | .2339 | 1948-1954 | |
| 14 | Hank Borowy | .2362 | 1942-1948 | |
| 15 | Jakie May | .2381 | 1918-1932 | |
| 16 | Christy Mathewson* | .2429 | 1900-1916 | |
| 17 | Bill Doak | .2431 | 1913-1929 | |
| 18 | Van Mungo# | .2474 | 1931-1954 | |
| 19 | Paul Derringer | .2485 | 1931-1952 | |
| 20 | Cy Young* | .2509 | 1890-1911 | |
| 21 | Dutch Leonard | .2525 | 1913-1925 | |
| 22 | Jesse Haines | .2554 | 1919-1938 | |
| 23 | Mort Cooper | .2561 | 1938-1947 | |
| 24 | Jeff Tesreau | .2604 | 1912-1918 | |
| 25 | Joe Wood | .2612 | 1908-1922 | |
| 26 | Babe Ruth* | .2617 | 1914-1935 | |
| 27 | Rube Waddell* | .2624 | 1897-1910 | |
| 28 | Charles Bender* | .2626 | 1903-1924 | |
| 29 | Bill Hallahan | .2640 | 1926-1941 | |
| 30 | Barney Morris | .2647 | 1932-1947 | |
| 30 | Jack Quinn | .2647 | 1909-1932 | |
| 32 | Gentry Jessup# | .2698 | 1940-1954 | |
| 33 | Allie Reynolds# | .2700 | 1942-1954 | |
| 34 | Wilbur Cooper | .2707 | 1912-1926 | |
| 35 | Carl Hubbell* | .2720 | 1928-1948 | |
| 36 | Herb Pennock | .2727 | 1912-1934 | |
| 37 | Deacon Phillippe | .2741 | 1899-1911 | |
| 38 | Lefty Grove* | .2742 | 1925-1945 | |
| 39 | Walter Johnson* | .2803 | 1907-1927 | |
| 40 | Lefty Gomez | .2817 | 1930-1942 | |
| 41 | Satchel Paige | .2821 | 1927-1951 | |
| 42 | Otto Hess | .2845 | 1902-1914 | |
| 43 | Waite Hoyt | .2850 | 1919-1944 | |
| 43 | Red Ames* | .2850 | 1903-1919 | |
| 45 | Mordecai Brown* | .2926 | 1903-1916 | |
| 46 | Fred Toney | .2937 | 1914-1923 | |
| 47 | Hod Eller | .2959 | 1917-1920 | |
| 48 | Sam Streeter | .2974 | 1921-1936 | |
| 49 | Johnny Allen | .2976 | 1932-1942 | |
| 50 | Tom Zachary | .3008 | 1920-1936 | |
| 51 | Bill Bernhard | .3071 | 1899-1907 | |
| 52 | Jack Pfiester | .3191 | 1904-1911 | |
| 53 | Vean Gregg | .3298 | 1911-1925 | |
| 54 | Dave Brown | .3360 | 1919-1925 | |
| 55 | Rube Marquard | .3378 | 1908-1925 | |
| 56 | Al Hollingsworth | .3758 | 1935-1947 |
