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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | BB | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Charles Bender# | 37 | 1903-1915 | |
| 2 | Vean Gregg# | 30 | 1911-1915 | |
| 3 | Rube Waddell | 25 | 1897-1910 | |
| 4 | Claude Hendrix# | 18 | 1911-1915 | |
| 4 | Christy Mathewson# | 18 | 1900-1915 | |
| 6 | Dutch Leonard# | 17 | 1913-1915 | |
| 6 | Rube Marquard# | 17 | 1908-1915 | |
| 8 | Jack Coombs# | 15 | 1906-1915 | |
| 9 | Orval Overall | 14 | 1905-1913 | |
| 10 | Red Ames# | 13 | 1903-1915 | |
| 11 | Cy Young | 12 | 1890-1911 | |
| 12 | Frank Lange | 11 | 1910-1913 | |
| 12 | George McConnell# | 11 | 1912-1915 | |
| 12 | George McQuillan# | 11 | 1907-1915 | |
| 12 | Jeff Tesreau# | 11 | 1912-1915 | |
| 12 | Joe Wood# | 11 | 1908-1915 | |
| 17 | Bill Bernhard | 10 | 1899-1907 | |
| 17 | Mordecai Brown# | 10 | 1903-1915 | |
| 17 | George Mullin | 10 | 1902-1913 | |
| 17 | Eddie Plank# | 10 | 1901-1915 | |
| 17 | Jesse Tannehill | 10 | 1894-1910 | |
| 22 | Jack Chesbro | 9 | 1899-1909 | |
| 23 | Frank Smith | 8 | 1904-1911 | |
| 24 | Otto Hess | 7 | 1902-1914 | |
| 24 | Win Kellum | 7 | 1901-1905 | |
| 24 | Joe Lake | 7 | 1908-1913 | |
| 24 | Jack Pfiester | 7 | 1904-1911 | |
| 24 | Joe Williams# | 7 | 1907-1915 | |
| 29 | Weldon Henley | 6 | 1903-1907 | |
| 29 | Addie Joss | 6 | 1902-1910 | |
| 29 | Charlie Smith | 6 | 1903-1914 | |
| 29 | Doc White | 6 | 1901-1912 | |
| 29 | George Winter | 6 | 1901-1908 | |
| 34 | Harry Krause | 5 | 1908-1911 | |
| 34 | Lefty Leifield# | 5 | 1905-1913 | |
| 34 | Earl Moore | 5 | 1901-1913 | |
| 37 | Babe Adams# | 4 | 1906-1915 | |
| 37 | Ray Collins | 4 | 1909-1915 | |
| 37 | George Cuppy | 4 | 1892-1901 | |
| 37 | Marty McHale# | 4 | 1913-1915 | |
| 37 | Kid Nichols* | 4 | 1890-1906 | |
| 37 | Babe Ruth# | 4 | 1914-1915 | |
| 37 | Jimmy Ryan | 4 | 1885-1903 | |
| 44 | Bill Donovan# | 3 | 1898-1914 | |
| 44 | Tom Hughes# | 3 | 1906-1915 | |
| 44 | Tom Hughes | 3 | 1900-1913 | |
| 44 | Jock Menefee | 3 | 1892-1903 | |
| 44 | Deacon Phillippe | 3 | 1899-1911 | |
| 44 | Bill Phyle | 3 | 1898-1906 | |
| 44 | George Prentiss | 3 | 1901-1902 | |
| 44 | Dave Williams | 3 | 1902-1902 | |
| 52 | Eddie Cicotte# | 2 | 1906-1915 | |
| 52 | Russ Ford | 2 | 1909-1913 | |
| 52 | Ed Killian | 2 | 1903-1910 | |
| 52 | Hank Robinson# | 2 | 1911-1915 | |
| 56 | Gus Dorner | 1 | 1902-1909 | |
| 56 | George Ferguson | 1 | 1906-1910 | |
| 56 | Frank Foreman | 1 | 1884-1902 | |
| 56 | Rube Foster# | 1 | 1913-1915 | |
| 56 | Norwood Gibson | 1 | 1903-1906 | |
| 56 | Sam Leever | 1 | 1898-1909 | |
| 56 | Carl Mays# | 1 | 1915-1915 | |
| 56 | Jack Rowan | 1 | 1906-1914 | |
| 56 | Dummy Taylor | 1 | 1900-1908 | |
| 56 | Hooks Wiltse | 1 | 1904-1914 | |
| 66 | Nick Altrock# | 0 | 1898-1915 | |
| 66 | Fred Anderson# | 0 | 1909-1915 | |
| 66 | Joe Bush# | 0 | 1912-1915 | |
| 66 | Frank Corridon | 0 | 1906-1909 | |
| 66 | Cy Falkenberg# | 0 | 1904-1915 | |
| 66 | Ted Lewis | 0 | 1896-1901 | |
| 66 | Fred Mitchell | 0 | 1902-1911 | |
| 66 | Ed Reulbach# | 0 | 1905-1915 | |
| 66 | Ed Siever | 0 | 1901-1908 | |
| 66 | Paul Strand# | 0 | 1913-1915 | |
| 66 | Snake Wiltse | 0 | 1901-1903 |
