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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | W | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Charles Bender# | 7 | 1903-1915 | |
| 1 | Christy Mathewson# | 7 | 1900-1915 | |
| 3 | Jesse Tannehill | 6 | 1894-1910 | |
| 4 | Babe Adams# | 5 | 1906-1915 | |
| 5 | Mordecai Brown# | 4 | 1903-1915 | |
| 5 | Rube Waddell | 4 | 1897-1910 | |
| 7 | Red Ames# | 3 | 1903-1915 | |
| 7 | Hooks Wiltse | 3 | 1904-1914 | |
| 7 | Joe Wood# | 3 | 1908-1915 | |
| 7 | Cy Young | 3 | 1890-1911 | |
| 11 | Jack Chesbro | 2 | 1899-1909 | |
| 11 | Claude Hendrix# | 2 | 1911-1915 | |
| 11 | Addie Joss | 2 | 1902-1910 | |
| 11 | Harry Krause | 2 | 1908-1911 | |
| 11 | Dutch Leonard# | 2 | 1913-1915 | |
| 11 | Rube Marquard# | 2 | 1908-1915 | |
| 11 | George McConnell# | 2 | 1912-1915 | |
| 11 | Kid Nichols* | 2 | 1890-1906 | |
| 11 | Orval Overall | 2 | 1905-1913 | |
| 11 | Deacon Phillippe | 2 | 1899-1911 | |
| 11 | Eddie Plank# | 2 | 1901-1915 | |
| 11 | Joe Williams# | 2 | 1907-1915 | |
| 23 | Bill Bernhard | 1 | 1899-1907 | |
| 23 | Jack Coombs# | 1 | 1906-1915 | |
| 23 | Bill Donovan# | 1 | 1898-1914 | |
| 23 | Russ Ford | 1 | 1909-1913 | |
| 23 | Vean Gregg# | 1 | 1911-1915 | |
| 23 | Tom Hughes | 1 | 1900-1913 | |
| 23 | Ed Killian | 1 | 1903-1910 | |
| 23 | Joe Lake | 1 | 1908-1913 | |
| 23 | Frank Lange | 1 | 1910-1913 | |
| 23 | George McQuillan# | 1 | 1907-1915 | |
| 23 | George Mullin | 1 | 1902-1913 | |
| 23 | Jack Pfiester | 1 | 1904-1911 | |
| 23 | Hank Robinson# | 1 | 1911-1915 | |
| 23 | Babe Ruth# | 1 | 1914-1915 | |
| 23 | Charlie Smith | 1 | 1903-1914 | |
| 23 | Frank Smith | 1 | 1904-1911 | |
| 23 | Dummy Taylor | 1 | 1900-1908 | |
| 23 | Jeff Tesreau# | 1 | 1912-1915 | |
| 23 | Doc White | 1 | 1901-1912 | |
| 23 | Snake Wiltse | 1 | 1901-1903 | |
| 43 | Nick Altrock# | 0 | 1898-1915 | |
| 43 | Fred Anderson# | 0 | 1909-1915 | |
| 43 | Joe Bush# | 0 | 1912-1915 | |
| 43 | Eddie Cicotte# | 0 | 1906-1915 | |
| 43 | Ray Collins | 0 | 1909-1915 | |
| 43 | Frank Corridon | 0 | 1906-1909 | |
| 43 | George Cuppy | 0 | 1892-1901 | |
| 43 | Gus Dorner | 0 | 1902-1909 | |
| 43 | Cy Falkenberg# | 0 | 1904-1915 | |
| 43 | George Ferguson | 0 | 1906-1910 | |
| 43 | Frank Foreman | 0 | 1884-1902 | |
| 43 | Rube Foster# | 0 | 1913-1915 | |
| 43 | Norwood Gibson | 0 | 1903-1906 | |
| 43 | Weldon Henley | 0 | 1903-1907 | |
| 43 | Otto Hess | 0 | 1902-1914 | |
| 43 | Tom Hughes# | 0 | 1906-1915 | |
| 43 | Win Kellum | 0 | 1901-1905 | |
| 43 | Sam Leever | 0 | 1898-1909 | |
| 43 | Lefty Leifield# | 0 | 1905-1913 | |
| 43 | Ted Lewis | 0 | 1896-1901 | |
| 43 | Carl Mays# | 0 | 1915-1915 | |
| 43 | Marty McHale# | 0 | 1913-1915 | |
| 43 | Jock Menefee | 0 | 1892-1903 | |
| 43 | Fred Mitchell | 0 | 1902-1911 | |
| 43 | Earl Moore | 0 | 1901-1913 | |
| 43 | Bill Phyle | 0 | 1898-1906 | |
| 43 | George Prentiss | 0 | 1901-1902 | |
| 43 | Ed Reulbach# | 0 | 1905-1915 | |
| 43 | Jack Rowan | 0 | 1906-1914 | |
| 43 | Jimmy Ryan | 0 | 1885-1903 | |
| 43 | Ed Siever | 0 | 1901-1908 | |
| 43 | Paul Strand# | 0 | 1913-1915 | |
| 43 | Dave Williams | 0 | 1902-1902 | |
| 43 | George Winter | 0 | 1901-1908 |
